Can taking progesterone cure endometrial thickening?

Taking progesterone can treat endometrial thickening. Progesterone is a progesterone drug that can inhibit excessive endometrial proliferation by regulating estrogen levels. It is suitable for situations caused by simple endometrial thickening or hormone imbalance. However, it must be used under the guidance of a doctor and the possibility of malignant lesions must be ruled out.

Progesterone counteracts the effects of estrogen, prompting the thickened endometrium to enter the secretory phase and shed, thus improving the abnormal thickening. Commonly used clinical drugs include progesterone capsules, dydrogesterone tablets, medroxyprogesterone acetate tablets, etc. During treatment, regular ultrasound monitoring of changes in the endometrium is required. Usually, withdrawal bleeding occurs 10 to 14 days after medication, completing the endometrial stripping process. In patients with anovulatory uterine bleeding, progesterone can help establish a regular menstrual cycle.

But progesterone is not suitable for all cases of endometrial thickening. If the thickening is caused by endometrial polyps, submucosal fibroids, or endometrial cancer, surgery or a combination of treatments may be needed. Complex hyperplasia caused by long-term unopposed estrogen stimulation may require higher doses of progestins or intrauterine sustained-release systems. Side effects such as breast swelling and pain, dizziness, etc. may occur during medication. Sudden and abnormal bleeding requires prompt medical treatment.

During progesterone treatment, you should maintain a regular schedule and avoid cold, spicy foods. Endometrial conditions need to be reviewed 3-6 months after treatment, and patients with refractory thickening may need diagnostic dilation and curettage to clarify the pathology. People with a history of hypertension and thrombosis should use the drug with caution, and it is contraindicated in lactating women. It is recommended to formulate an individualized plan under the guidance of a gynecologist, and do not adjust the dosage yourself.