What is the cause of polycystic ovary syndrome

Polycystic ovary syndrome may be caused by genetic factors, environmental factors, endocrine disorders, insulin resistance, obesity and other reasons.

1. Genetic factors

Polycystic ovary syndrome tends to cluster in families, and having a mother or sister who has the disease increases the risk of the disease. It may be related to genetic mutations or genetic susceptibility, which affects follicular development and hormone secretion. For patients with suspected genetic factors, it is recommended to complete family history investigation and conduct genetic testing if necessary.

2. Environmental factors

Long-term exposure to environmental endocrine disruptors such as bisphenol A and pesticides may interfere with hormone balance. Excessive long-term mental stress, disordered work and rest, etc. can also affect the function of the hypothalamus-pituitary-ovary axis. Reducing the use of plastic products and regular sleep can help improve symptoms.

3. Endocrine disorders

Hypothalamic-pituitary-ovarian axis dysfunction leads to an abnormal ratio of luteinizing hormone and follicle-stimulating hormone and excessive secretion of androgens. Patients often present with symptoms such as oligomenorrhea, hirsutism, and acne. Your doctor may recommend regular review of hormone levels and, if necessary, hormone adjustment treatment.

4. Insulin resistance

Insulin resistance stimulates the ovaries to produce excess androgens while reducing sex hormone binding globulin levels. Patients may develop symptoms such as acanthosis nigricans and weight gain. Lifestyle interventions to control blood sugar and improve insulin sensitivity are important.

5. Obesity

Excess adipose tissue will promote the conversion of androgens into estrogens and aggravate endocrine disorders. Obese patients often have more obvious symptoms, and losing 5%-10% of their weight can significantly improve their symptoms. Reasonable diet control and moderate exercise are required.

Patients with polycystic ovary syndrome should establish a healthy lifestyle, maintain a balanced diet and control their weight. Choose low-glycemic index foods such as oats and brown rice in moderation, and avoid high-sugar and high-fat diets. Do at least 150 minutes of aerobic exercise every week, such as brisk walking, swimming, etc. Get enough sleep and manage stress levels. Regularly monitor blood sugar, blood lipids and other indicators to detect metabolic abnormalities in a timely manner. If symptoms worsen or menstrual irregularities occur, you should seek medical treatment promptly. The doctor will develop an individualized treatment plan based on the specific situation.