Is blood drawn for male chromosome test?

Checking the chromosomes is to check whether there are any abnormalities in the number or structure of the sex chromosomes. Standard value for men: 46, XY ； Lady: 46, XX. The main method is various sex chromosome banding analysis. Go to a reliable hospital to check it out. The doctor can help you check it out, and most doctors will explain it to you in detail.

1How to actually check sex chromosomes

For peripheral blood sex chromosomes, the checking process is generally: Carry out venous blood test on an empty stomach in the morning - Heparin anticoagulation - Peripheral blood reticulocyte shaping (37 degrees Celsius, 72 hours) - Cells are obtained by hypotonic method, fixed with fixative solution, and made into cell suspension - Producer, G The banding technology is either R banding or C banding - manual observation and analysis under the microscope (choose 20 to 50 late cell division phases with good dispersion) - report the results, take pictures under the microscope, analyze on the machine and convert them into text and picture reports - review and sign reports.

2 Check the clinical manifestations of chromosomes

1. Abnormal number and shape of chromosomes

(1) X chromosome deletion Turner syndrome: 45, there are 45 X sex chromosomes and only 1 X sex chromosome. The gas meter is female, but the sex hormones are underdeveloped, and the growth and development of secondary sex characteristics are delayed or underdeveloped. It is brief, with low-set ears, high palate, micrognathia, low posterior hairline, short neck, webbed neck, shield-shaped chest, wide breast distance, cubital valgus and possible slight shortcomings in IQ.

There are also chimeras with a karyotype of 45, X/46, XX； X sex chromosome digger extension arm missing ； Missing short arm of X sex chromosome ； The long and short arms of the X sex chromosome are missing ； Circular X sex chromosome ； X sex chromosome diggers and long arms, iso-arm sex chromosomes and X sex chromosomes and autosomal translocations may also have mild and severe manifestations of Turner syndrome.

(2) There are too many X sex chromosomes 47, XXX48, XXXX49, XXXXX and their chimeras with any normal chromosomes. Gas meters are more common in women, some have sex hormone dysplasia, and some have no obvious abnormalities and have reproductive function.

(3) Too many Y chromosomes and abnormal Klinefelter syndrome； 47, XXY patients are men. Most of them are tall and burly, with small and hard male testicles. They are lacking in growth and development. They have a female body shape, sparse hair, long arms and legs, and may have a slow IQ.

47. The XYY karyotype is rarer than the above. The patients are men. Most of them are tall, provocative, have weak IQs, and may have mental illness and disciplinary behavior. There are also a large number of people who have no clinical abnormalities.

(4) Hermaphroditism: Patients with true hermaphroditism have male testicles and uterine and ovarian tissue. Its body shape, secondary sexual characteristics and reproductive organs are both female and male. Most of the chromosomes have a karyotype of 46, XX, and a few may have 46, XY or 46, XX/46, XY, 45, X/46, XY, etc. chimeras.

Patients with testicular virilization syndrome appear to be normal women but have XY chromosomes and male testicular tissue. In patients with XY sex hormone dysplasia, the sex hormones and secondary sexual characteristics are usually underdeveloped as in Turner syndrome.