Causes of endometrial thickness

Endometrial thickening may be caused by endocrine disorders, endometrial polyps, endometrial hyperplasia, endometrial cancer, long-term estrogen stimulation, etc. Endometrial thickening usually manifests as abnormal menstruation, abnormal vaginal bleeding, infertility and other symptoms, and can be intervened through drug treatment, surgical treatment and other methods.

1. Endocrine disorders

Diseases such as polycystic ovary syndrome and thyroid dysfunction may cause estrogen to be continuously secreted without progesterone opposition. This kind of situation may be accompanied by symptoms of elevated androgens such as acne and hirsutism. You can use progesterone capsules, dydrogesterone tablets and other progesterone drugs as directed by your doctor to regulate the cycle. If necessary, you need to combine it with metformin tablets to improve insulin resistance.

2. Endometrial polyps

Chronic inflammation or hormonal stimulation may trigger localized overgrowth of the endometrium to form polyps. Patients often have intermenstrual spotting or prolonged menstrual bleeding, and hysteroscopic polypectomy is the main treatment. After surgery, a levonorgestrel sustained-release intrauterine system can be used for a short period of time to prevent recurrence.

3. Endometrial hyperplasia

Long-term anovulatory menstrual cycles make the endometrium continue to be stimulated by estrogen, and simple or complex hyperplasia may occur. The clinical manifestations are increased menstrual flow and prolonged menstrual period. Histopathological diagnosis needs to be obtained through diagnosis and curettage. For mild cases, medroxyprogesterone acetate tablets can be taken orally. For severe atypical hyperplasia, hysterectomy should be considered.

4. Endometrial cancer

People with metabolic abnormalities such as obesity and diabetes are prone to estrogen-dependent endometrial lesions. Typical symptoms are postmenopausal bleeding or perimenopausal menstrual disorders. Diagnosis requires segmented diagnosis and curettage. Early-stage patients can choose extrafascial total hysterectomy combined with pelvic lymph node dissection.

5. Long-term estrogen stimulation

Irregular exogenous estrogen supplementation or estrogen-secreting tumors may lead to continued intimal proliferation. Such patients need to evaluate the status of target organs such as the breast and uterus, promptly stop taking estrogen preparations or treat the primary tumor, and if necessary, use ovulation induction drugs such as Clomiphene Citrate Tablets to restore the menstrual cycle.

It is recommended to maintain a regular schedule to avoid endocrine disorders and control body weight within a normal range to reduce peripheral conversion of estrogen. Perform annual gynecological examinations and ultrasound to monitor the condition of the endometrium, and seek medical advice promptly if changes in the menstrual cycle or abnormal bleeding occur. Pay attention to limiting the intake of high-fat foods, and increase broccoli, soy products and other foods containing phytoestrogen regulating ingredients in an appropriate amount. Avoid taking estrogen-containing health products or drugs by yourself. All treatment plans must be formulated under the guidance of a specialist.