How to treat ovarian cystadenocarcinoma

Ovarian cystadenocarcinoma can be comprehensively intervened through surgical treatment, chemotherapy, targeted therapy, immunotherapy and auxiliary treatment with traditional Chinese medicine.

1. Surgical treatment

Radical surgery is the preferred treatment for ovarian cystadenocarcinoma, including total bilateral adnexectomy, omentectomy, and pelvic lymph node dissection. Fertility-preserving surgery can be used for early-stage patients, but strict evaluation of tumor stage and degree of differentiation is required. Postoperative pathological results will guide the selection of subsequent adjuvant treatment options.

2. Chemotherapy

After surgery, a combination chemotherapy regimen containing platinum drugs is routinely used, and paclitaxel injection combined with carboplatin injection is commonly used. For patients with recurrence, second-line drugs such as doxorubicin liposome injection or topotecan capsules can be used. During chemotherapy, blood routine and liver and kidney functions need to be monitored regularly, and if necessary, recombinant human granulocyte stimulating factor injection can be used to prevent bone marrow suppression.

3. Targeted therapy

For patients with BRCA gene mutations, PARP inhibitors such as olaparib tablets can be used. Bevacizumab injection can be used to inhibit tumor angiogenesis. Targeted drugs usually need to be used in conjunction with genetic testing results and may cause adverse reactions such as hypertension and proteinuria, which require close monitoring.

4. Immunotherapy

PD-1 inhibitors such as pembrolizumab injection are suitable for advanced patients with high microsatellite instability or mismatch repair deficiency. PD-L1 expression detection needs to be performed before treatment, and adverse reactions such as immune-related pneumonia and colitis may occur during use. Some patients can try new immunotherapy methods such as tumor-infiltrating lymphocyte therapy.

5. Traditional Chinese Medicine Assisted Treatment

The use of traditional Chinese medicine preparations such as Shenqi Fuzheng Injection and Kanglaite Injection can reduce the side effects of radiotherapy and chemotherapy. Acupuncture can help relieve cancer pain and chemotherapy-induced vomiting. Traditional Chinese medicine decoctions need to be prepared according to individual constitution to avoid interactions with targeted drugs.

Patients with ovarian cystadenocarcinoma should maintain a balanced diet after surgery, supplement appropriate amounts of high-quality protein such as fish and eggs, and limit the intake of high-fat foods. Carry out low-intensity exercises such as walking and Tai Chi according to your physical condition, and avoid strenuous activities. Regularly review tumor markers and imaging examinations, and pay attention to signs of recurrence such as lower limb edema and abdominal distension. Maintain a regular schedule and an optimistic attitude, and seek psychological counseling support when necessary. All medications must be used strictly in accordance with medical advice, and treatment plans must not be adjusted on your own.